Comprehensive Arrhythmia Panel

Cardiac Arrhythmia

What is Cardiac Arrhythmia?

This is a disruption of the heart’s natural rhythm.

There are many different subtypes of arrhythmia, including: arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C), familial atrial fibrillation, Brugada syndrome, progressive cardiac conduction disease, catecholaminergic polymorphic ventricular tachycardia, long QT syndrome and short QT syndrome.

What causes Cardiac Arrhythmia?

There are a number of causes of Cardiac Arrhythmia, from trauma and infection, to structural abnormalities and genetic disorders. Genetic forms of arrhythmia can begin as early as childhood or adolescence, but more often develop in adulthood.

Hereditary cardiac arrhythmia can be inherited in both an autosomal dominant or recessive manner, though most condition are inherited in autosomal dominant manner. This means that individuals with genetic mutations that cause arrhythmia have a 50 percent chance of passing the genetic mutation on to their children.

Why test for Cardiac Arrhythmia?

Identifying the genetic cause of Cardiac Arrhythmia with genetic testing is essential in confirming a diagnosis of a familial arrhythmia and providing information about symptoms associated with that type of arrhythmia, or what may be experienced in the future. Test results can also help patients make treatment decisions – surgical and other management decisions are personalized, and are sometimes based on genetic test results. Results of genetic testing can also identify family members who are at risk of developing an arrhythmia and allow them to seek preventative care.

Comphrehensive Arrhythmia Panel

Our Comprehensive Arrhythmia Panel carries out a sequence analysis of 30 genes that cause various Cardiac Arrhythmias. This genetic test is appropriate for anyone with a suspected genetic cause for arrhythmia.

How does it work?

The Comprehensive Arrhythmia Panel is a blood test ordered by your physician. Your DNA is extracted from the blood and analyzed by searching specifically for mutations in any genes that are associated with arrhythmias. The test takes approximately 10 weeks to complete, and the results will be sent to your physician, who will explain the test results to you.

We will need two tubes of blood (about 7 to 10ml) and a signed consent form from you to send to the laboratory. We recommend genetic counselling before genetic tests are ordered to discuss the implications of the testing and potential results.

If you would like more information or advice on any of our tests and services, please contact us at +65 6336 2050 or