Breast cancer is the most commonly diagnosed cancer in women. In Singapore, more than 25 percent of all cancers diagnosed in women are breast cancers. While the majority of breast cancers occur sporadically, up to 10 percent of such cancers have a hereditary link.

Why get tested for BRCA?

If there is a family history of breast cancer, genetic testing can help identify your risks, along with learning about such risks for other family members and future generations. This could help you make informed decisions about your future, including taking steps to reduce your cancer risks.

About the test

The BRCA 1 and BRCA 2 genes are tumor suppressor genes that code for proteins that allow normal cell function. Mutation in these genes removes their normal protective effects allowing cancer to develop early. Research has found that up to 50 percent of hereditary breast cancer can be attributed to mutations in BRCA 1 & 2 genes. There is also an increased risk of developing other cancer types including prostate cancer for male carriers.

The BRCA 1 and BRCA 2 test identifies mutations in these two genes. It is a blood or saliva test you can order though your physician. Your DNA is extracted from the blood or saliva sample and analyzed. The results will be sent to your physician, who will explain the test results to you.

We will need either two tubes of blood (about 3ml each) or 10ml of saliva sample, and a signed consent form from you to send to the laboratory. We recommend genetic counseling before genetic tests are ordered to discuss the implications of the testing and potential results.

If you would like more information or advice on any of our tests and services, please contact us at +65 6336 2050 or