Verifi® Non-Invasive Prenatal Test (NIPT)

Helping you know more about your baby

During pregnancy there is a lot of new information to learn and decisions to make. There are currently many options to help you learn about the health of your baby, but which ones are best for you and how do you decide?

What is Verifi® Non-Invasive Prenatal Testing?

Verifi® Non-invasive Prenatal Testing (NIPT) is one of the newest options to screen for some of the most common chromosome abnormalities that can affect the health and development of your baby. Common examples of chromosome abnormalities include, Down syndrome (trisomy 21) which is found is 1 in 1000 babies born, and Edwards syndrome (trisomy 18).

How is the test done?

Verifi® NIPT is a blood test that is non-invasive and does not have a risk of miscarriage. Your doctor collects one tube of blood from the mother, and ships it to our laboratory. Your doctor usually receives the results within 2 weeks.

What does NIPT screen for?

Verifi® NIPT is able to screen your baby for more of the most common chromosome abnormalities than any other screening option, including serum screening. You also have the ability to choose how many or how few conditions you screen for based on your concerns.
Below are the options you can choose:

Testing option What this option tests for Availability
* Option may not be available in all countries/regions.
** Current chromosome microdeletion syndromes included in Verifi® are 22q11 deletion (DiGeorge), 15q11 deletion (Angelman/ Prader-Willi), 1p36 deletion, 4p- (Wolf-Hirschhorn), 5p- (Cri-du-chat).
Common Aneuploidies Monosomy or trisomy of chromosomes 21, 18, 13 (also known as Down syndrome, Edwards syndrome, and Patau syndrome) Singletons & Twins
Sex Chromosomes Determines the sex of the baby and if there are too few or too many sex chromosomes (such as Turner syndrome or Klinefelter syndrome)* Singletons
Additional Aneuploidies Trisomies 9 and 16 Singletons
Microdeletion Panel Common small chromosome deletions causing birth defects and learning difficulties** Singletons

How accurate is the Verifi® NIPT?

Verifi® NIPT can provide more accurate information about your baby, earlier and easier than other screening and testing options. However, there is always a small possibility of a false positive or false negative test. Unfortunately no one or combination of tests can guarantee a healthy baby. NIPT is a screening test, designed to provide you with some information about your baby, but it is limited. If a concern for a chromosome abnormality is identified, additional diagnostic testing, such as CVS or amniocentesis, is recommended before making any medical management decisions.

Is NIPT right for you?

Prenatal screening and testing can give you a lot of information to think about, including things you may not have expected. Before pursuing NIPT or any other prenatal screening, you and your partner should discuss the following questions. You may also discuss these questions further with your doctor before testing.

  • What information do I/we want to learn from this test?
  • What information can the test give me?
  • What information can’t the test give me?
  • What would I/we do with the results?
  • What would I/we do if the results are abnormal?
  • Would I/we consider doing more testing if the results are abnormal?
  • Would abnormal results affect how I/we would manage the pregnancy?

Common reasons women are offered prenatal screening or testing include if you fit any of the following:

  • Considered advanced maternal age. (35 years or older for a single pregnancy, 32 years or older for a twin pregnancy.)
  • Had another abnormal prenatal scan.
  • A concern or abnormality was found on ultrasound.
  • Have a personal family history of chromosome trisomy 21, 18, 13, or sex chromosome abnormality.

What should I do next?

There are many different tests and screens available during pregnancy. It is important for you to decide what information you want to know about you and your baby, and consider how you would use this information.
If you are interested in the Verifi® NIPT, or have more questions about your options, speak with your doctor.

If you would like more information or advice on any of our tests and services, please contact us at +65 6336 2050 or info@asia-genomics.com.